Jeffrey Neul, MD, PhD, is the Director of the Vanderbilt Kennedy Center at Vanderbilt University Medical Center and Annette Schaffer Eskind Chair and Professor of Pediatrics, Pharmacology, and Special Education at Vanderbilt University. Dr. Neul’s research focuses on neurodevelopmental disorders with a genetic cause, specifically on Rett syndrome and related disorders. His work spans from laboratory based basic and translational work using animal and cellular models of disease, to clinical research on the natural history of disease progression and clinical trials in these disorders.
Dr. Neul is currently Principal Investigator of an NIH/NICHD study (R01HD083181) that focuses on preclinical development of outcome measures and biochemical biomarkers in Rett syndrome, and the Administrative Head of an NIH/NICHD natural history study of Rett syndrome, MECP2 Duplications, and Rett-related Disorders (U54HD061222) which seeks to establish the natural history and enable clinical-trial readiness in these disorders. He is also the PI of the Eunice Kennedy Shriver Intellectual and Developmental Disorder Research Center at Vanderbilt University (U54HD083211). Dr. Neul has been active in all industry-sponsored clinical trials in Rett syndrome, has led efforts to establish the clinical criteria for the diagnosis of Rett syndrome, create clinical trial outcome measures in Rett syndrome, and is currently the holder of the Federal Drug Administration Investigational New Drug designation for oral ketamine in Rett syndrome. His work has been published in various journal including Nature, Science Translational Medicine, Annals of Neurology, Neurology, Human Molecular Genetics.
Dr. Neul received the Philip R. Dodge Young Investigator Award from the Child Neurology Society and the Circle of Angels from the International Rett Syndrome Foundation. He was elected to the American Society for Clinical Investigation. He served on the Scientific Selection Committee, Award Selection Committee, and Research Committee of the Child Neurology Society, and on the Medical Advisory Board for the International Rett Syndrome Foundation and the International FoxG1 Foundation.
Dr. Neul completed his undergraduate education in Chemistry at the University of Illinois. He received his medical degree and PhD in Developmental Biology from the University of Chicago, and completed child neurology residency at Baylor College of Medicine and Texas Children’s Hospital. He previously was the Division Chief of Child Neurology at University of California, San Diego and Rady Children’s Hospital San Diego. He currently practices Child Neurology at Monroe Carell Children’s Hospital at Vanderbilt University Medical Center.
Read more about Dr. Neul at https://vkc.mc.vanderbilt.edu/people/neul-jeffrey